Shimadzu RF-20Axs

This used Shimadzu RF-20Axs is a high sensitivity fluorescence detector designed for Shimadzu Prominence and Nexera HPLC systems, offering enhanced optical sensitivity compared to the standard RF-20A model. It employs a xenon flash lamp along with precise excitation and emission wavelength control to detect trace concentrations of fluorescent compounds, supporting analytical work that demands very low detection limits. The extra sensitivity of the Axs variant makes it especially useful for applications where sample concentration is limited or where regulatory detection thresholds are stringent. As part of an HPLC stack, the RF-20Axs receives column effluent and generates a proportional fluorescence signal that is captured by the system's data acquisition software for peak integration and quantitative reporting. It is frequently used in pharmaceutical bioanalysis, clinical research, and environmental monitoring where compounds such as pharmaceuticals, metabolites, or contaminants must be detected at nanogram or lower levels. The unit integrates smoothly alongside Shimadzu pumps, autosamplers, and column ovens to complete a validated analytical workflow. This detector is sold used and was pulled from an operating laboratory environment where it performed routine fluorescence detection duties. It is a strong choice for laboratories upgrading detection sensitivity on an existing Shimadzu LC system or building out a dedicated trace analysis method without the expense of purchasing new instrumentation.