Thermo Fisher Ion S5 XL

This used Thermo Fisher Ion S5 XL is a next generation sequencing platform built for laboratories that need fast, scalable results from targeted panels, exomes, and small genome sequencing projects. The system integrates semiconductor sequencing technology with automated data analysis, allowing labs to move from sample to annotated variant calls in a single day. It has been maintained as part of an active molecular biology workflow and is offered here in good operating condition. The Ion S5 XL supports a wide range of chip formats, giving users the flexibility to scale throughput up or down depending on project needs, from small gene panels to larger oncology and inherited disease panels. Its integrated software suite handles base calling, alignment, and variant analysis, reducing the need for extensive bioinformatics infrastructure on site. This makes it a strong fit for clinical research labs, academic sequencing cores, and diagnostic laboratories building out NGS capacity without committing to a full production-scale sequencer. Buyers acquiring this unit gain access to a proven sequencing platform with a large installed base and extensive published protocols, which shortens the learning curve for new operators. As a used system, it represents a lower cost entry point into semiconductor-based sequencing while still providing the throughput and turnaround needed for routine panel work. The unit is sold as is and buyers are encouraged to arrange qualification testing with their own reagents prior to production use.