Bio-Rad PTC-100

This used Bio-Rad PTC-100 programmable thermal controller is a classic workhorse thermal cycler that has supported countless PCR protocols in molecular biology labs since its introduction. Originally developed by MJ Research and later part of the Bio-Rad thermal cycler lineup, the PTC-100 uses a Peltier-based heating and cooling block to drive standard amplification protocols with dependable temperature control. Its straightforward keypad interface and menu-driven programming make it easy to set up and run standard PCR cycles without a computer connection. The PTC-100 was widely used for routine DNA amplification, cloning workflows, and general molecular biology applications where a dedicated, no-frills thermal cycler was needed. Its rugged construction and simple mechanical design have kept many units in service well beyond their original expected lifespan, and its heated lid options helped standardize reaction volumes by reducing evaporation. Labs appreciated the instrument for its consistency and its ability to run overnight protocols unattended. This pre-owned PTC-100 has been checked for proper cycling function and is offered as an affordable option for teaching labs, backup cycling capacity, or facilities running legacy protocols that do not require real-time fluorescence detection. It is a solid choice for anyone who needs reliable basic PCR performance on a tight budget.